The Rise Of Plant Power With Health Aura

 Consumers of all ages hope to eat more on the health attributes of "natural functions" of plants. Therefore, the innovation of plant-based ingredients is booming in the food and beverage industry. Curcumin.The frequency of use of green tea extract, hemp, jackfruit and other raw materials is higher and higher year by year, and the plant-based market is growing at an exponential level. More and more enterprises are using these ingredients to meet the growing demand of consumers.

Curcumin: focus on antiviral and cognitive health

  A new review, co-authored by Dr. Muhammed Majeed, founder of Sabina (Sabinsa), and a number of other scientists, explores the potential impact of curcumin on COVID-19 infection. Based on the existing research data of curcumin and viral infection, this review lays a foundation for the study of curcumin as a possible treatment.

  This review summarizesthe results of curcumin in silica gel and animals infected with the virus. Novel coronavirus enters human cells through ACE2 receptors attached to its spiny protein, and the researchers speculate that curcumin can at least partially prevent the virus from entering, inferred from the study of silica gel docking.

  The review also cites a number of studies indicating that curcumin can potentially inhibit the entry of viruses into cells, inhibit the encapsulation of viruses and viral proteases, and regulate various cellular signaling pathways. The effective study of curcumin on pulmonary inflammation, fibrosis and edema, as well as the regulatory effect of curcumin on heart and kidney injury caused by viral infection were also cited.

  In all the reviewed studies, the antioxidant and anti-inflammatory properties of curcumin are the basis of its activity, but the biological mechanism of these effects has not yet been fully determined, and the study has been published in the Journal of Plant Therapy Research.

  In a 12-week study, 80 healthy men and women between the ages of 50 and 80 were supplemented with     Longvida curcumin, which was found to improve working memory while significantly reducing fatigue and stress responses. After 12 weeks of using series III, series 7 and the virtual Morris water maze test, the subjects' memory performance improved. In addition, in the 4th and 12th weeks, the fatigue score in turmerin group was lower, while tension, anger, confusion and total emotional disorder were significantly improved only in the 4th week.
  Based on past biomarker analysis, curcumin has shown a positive regulatory effect on several risk factors that can change cognitive decline, the researchers said. These include reducing inflammation, insulin in the blood, pre-diabetic blood glucose regulation related indicators and type 2 diabetes mellitus, these metabolic diseases involve cognitive decline and cognitive impairment. In general, there is growing evidence that curcumin is a candidate for the prevention of cognitive impairment and cognitive impairment.

The guard of skin:green tea polyphenols

  The main ingredient of green tea polyphenols is EGCG (Gallic catechin gallate). EGCG has been shown to have a variety of health benefits. Its characteristics, from antioxidants to anti-inflammation, are beneficial to cardiovascular health, cancer prevention, reducing the risk of cognitive impairment, improving diabetes, helping to lose weight and so on.

  EGCG has the characteristics of UV protection and may play a preventive role in the development of skin cancer. It is reported that EGCG treatment can reduce collagen synthesis and collagenase secretion in mice (24 hours later). Because ultraviolet induced intracellular damage is typical of affecting collagen synthesis and collagenase secretion levels.

  In addition, the damage induced by ultraviolet B was quantified by measuring the erythema induced by ultraviolet B in guinea pigs. EGCG was reported to significantly reduce erythema within 24 hours after irradiation.

   Another study also analyzed the effect of EGCG on (LCs) in epidermis Langerhans cells and described the decrease in the number of cells exposed to ultraviolet radiation. Histologic tests showed that compared with the control group, the skin LCs damage of the participants treated with EGCG decreased by 58%. The dose-dependent effect of green tea polyphenols was tested with different concentrations (1-10%). When the concentration is 2.5% or higher, it shows appropriate protective effect.

  These results are consistent with a recent study to detect the oxidative damage of DNA induced by ultraviolet radiation by measuring the depletion of CDla+ cells and the production of 8-hydroxy2-deoxyguanidine (8-0HdG) induced by ultraviolet radiation. 8.0HdG is related to ultraviolet induced nucleic acid modification.

  Compared with unirradiated skin, CDla+ cells decreased by 35 percent in green tea treated skin exposed to ultraviolet light. After irradiation, the treated skin decreased by 57.9%, which was similar to that of the untreated skin.

  The level of 8 OHdG in the skin exposed by green tea extract was not significantly different from that in the unirradiated skin. But the media-treated skin showed a higher level of 8  OHdG.

  In addition, EGCG is reported to reduce ultraviolet induced H2O2 and NO, production in dermis and epidermis that inhibit the infiltration of CD11b+ cells (CD11b+ is a marker of macrophage and neutrophil surface), which is an indicator of oxidative stress. EGCG can also inhibit the production of (LPO) in epidermis and have a positive effect on the level of other antioxidants (GSH).
  A similar study, involving the same type of mice, provided additional information on the extent to which EGCG induced apoptosis in tumor and non-tumor areas irradiated by UVB. After 20 weeks of UV- B irradiation, the mice were treated with EGCG once a day, 5 days a week for 18 weeks. This treatment led to the increase of apoptosis in 72% of non-malignant tumor cells and 56% of squamous cell carcinoma cells, but had no effect on proliferation or non-tumor areas.

Immune effect of Water extract from broccoli Seeds

  As we all know, the water extract of broccoli seeds has a good performance in anticancer, promoting detoxification and long-term antioxidant. Do you know its immune effect? The water extract of broccoli seeds contains radish glucosinolates, which are absorbed by human body and reacted with black mustard seed enzyme to produce sulforaphane. Sulforaphane not only has strong anticancer activity, but also has strong antioxidant capacity. It is recognized as one of the natural products with cancer prevention, anticancer and cosmetic effects. Sulforaphane is the most effective activating agent of human autoimmune system (Nrf2) pathway in food, which has a wide range of protective effects.
  Strengthening the defense response of antiviral hosts through nutritional supplementation is an effective means to resist influenza. Foreign studies have shown that short-term intake of broccoli bud homogenate can reduce the markers of virus replication in nasal lavage fluid cells after vaccinated with attenuated influenza virus (LAIM) live vaccine in smokers, because broccoli bud homogenate contains high concentration of radish thionein precursor, radish thionein is the most effective activating agent of human autoimmune system (Nrf2) pathway in food, which has a wide range of protective effects.

  Ingestion of broccoli bud homogenate in vivo or supplementation in epithelial cells can enhance the defense response of antiviral hosts. In addition, in addition to the effect on respiratory epithelial cells, it can also affect immune cells, including enhancing the scavenging effect of alveolar macrophages on bacteria, enhancing the lytic activity of natural killing (NK) cells, and increasing the overall activity of natural killing (NK) in mouse models.
  Domestic researchers have also done systematic research on the protective mechanism of sulforaphane immune function. In 2015, a study showed that both high and low doses of sulforaphane could significantly increase the thymic index and spleen index of cyclophosphamide (Cy), suggesting that sulforaphane had a definite protective effect on the immune organs suppressed by Cy and promoted the return to normal.

  The phagocytosis of abdominal macrophages was used as an index of nonspecific immune function, hemolysin test as a specific humoral immune index and lymphocytes transformation as a cellular immune index to observe the regulatory effects of two different doses of sulforaphane on the immune function of immunosuppressive mice. The results suggest that both high and low doses of sulforaphane can increase the phagocytic percentage and phagocytic index of abdominal macrophages and promote the formation of hemolysin. High dose of sulforaphane can significantly stimulate the transformation of lymphocytes. The immune excitatory effect of high dose sulforaphane was strong, while that of low dose group was relatively weak. It was considered that the immune protective effect of sulforaphane was positively correlated with the dose, and the immune excitatory effect would be enhanced with the increase of dose.

  The results showed that the content of radish glucosinolates in broccoli seeds was the highest. As the seeds germinate and grow, the content of radish glucosinolates will become less and less.